01 - In a large bowl, combine buttermilk and hot sauce. Add chicken pieces, turn to coat, cover, and refrigerate for at least 2 hours or overnight.
02 - Preheat oven to 450°F. In a large bowl, whisk flour, baking powder, baking soda, and salt. Cut in cold butter until mixture resembles coarse crumbs. Pour in buttermilk and stir just until combined. Turn dough onto a floured surface, gently pat to 3/4-inch thickness. Fold dough over itself 2-3 times for flakiness, then pat out again. Cut biscuits using a 2.5-inch round cutter. Place on a parchment-lined baking sheet.
03 - Bake 12–15 minutes until golden. Brush tops with honey or melted butter if desired.
04 - In a large bowl, combine flour, paprika, garlic powder, onion powder, cayenne, salt, and black pepper. Remove chicken from marinade, letting excess drip off. Dredge each piece well in seasoned flour.
05 - In a deep skillet or Dutch oven, heat 1.5 inches of oil to 350°F. Fry chicken in batches, turning occasionally, until golden brown and cooked through (internal temp 165°F), about 12–15 minutes per batch. Drain on a rack or paper towels.
06 - Serve warm fried chicken alongside hot buttermilk biscuits.